Dr. Stone

Ryusui Nanami is explicitly stated to be bisexual; in a Q&A segment at the end of manga chapter 90 (also relevant to the 'Ryusui Special' and Season 3 anime appearances), he expresses attraction to both men and women, saying, 'Every woman is a unique creature with her own charms. (The same goes for men!!)'. Senku Ishigami, the protagonist, is confirmed as aromantic and asexual (aroace) through his consistent distaste for physical intimacy and romantic overtures, referring to hugging as a 'worst-case scenario' (manga Chapter 56) and showing displeasure at a faked kiss (manga Chapter 107). Additionally, the relationship between antagonists Stanley and Dr. Xeno is heavily implied by fan communities and a manga cover describing them as 'soulmates,' suggesting a queer relationship that may be restricted by censorship.

During the 'Stone Wars' arc (Season 2), Senku's Kingdom of Science engages in battles against Tsukasa's Empire of Might, featuring confrontations with spears, swords, and other primitive weaponry. While direct bloodshed is often minimal, characters like Tsukasa and Hyoga are shown to use lethal force or have murderous intent, such as Tsukasa killing petrified adults to create his ideal world. The series also includes instances of gun violence, particularly in later seasons with the introduction of more advanced weaponry and characters like Stanley who are proficient in combat.

Kohaku, a primary female character, frequently appears in minimal attire such as a loincloth and an animal pelt top, with camera angles sometimes emphasizing her physique. Instances of male nudity occur for comedic effect, such as characters reacting to Taiju's general lack of clothing. In 'Dr. Stone: New World' Episode 8, Kohaku strategically kisses Senku to create the illusion of a romantic relationship and avoid capture, though Senku is uncomfortable with the physical intimacy. In a later season (Dr. Stone: Science Future, Episode 10), the character Luna explicitly asks Senku to be her boyfriend as a condition for providing medical assistance, establishing a romantic dynamic, albeit with Senku's known aromantic nature.

As the Kingdom of Science rebuilds, Senku and his allies successfully develop methods to produce alcohol (e.g., sake) as a scientific advancement. This leads to scenes where characters, including some who appear to be minors, are shown drinking and becoming drunk. For instance, a reviewer notes a scene in 'Dr. Stone Season 4 Episode 2' where characters are explicitly shown getting drunk during a process involving animal milking to create alcohol, with one character displaying an intoxicated reaction.

The core premise of humanity being instantly petrified and the characters awakening to a desolate 'Stone World' is inherently unsettling and intense. Antagonists like Tsukasa and Hyoga present significant physical and ideological threats, leading to tense confrontations and battles where characters' lives are explicitly at risk. For example, Tsukasa's initial actions of systematically shattering petrified adults he deems undesirable and Hyoga's ruthless fighting style create moments of genuine peril and suspense during conflicts such as the 'Stone Wars'.